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Once activated, SIRT1 and AMPK produce beneficial effects on glucose homeostasis and insulin action. Keto diet participants have said that they no longer feel hungry as frequently. Finally, although researchers theorize that exogenous ketones may help with weight and fat loss, only one clinical trial has found a link between exogenous ketones and appetite suppression in humans. You will be considerably more energetic and healthier when cooking your own keto friendly food, rather than buying supposedly keto foods off the shelf.